Author: James Fishman

A rather strange article recently published in the Journal of Neurology, Neurosurgery and Psychiatry shows that large amounts of caffeine just might help you to prevent multiple sclerosis. Two studies were conducted. One from Karolinska Institute in Stockholm, Sweden, looked at 1620 adults with MS and 2788 without the disease. The second study, conducted through Johns Hopkins University in Maryland and the University of California, Berkeley looked at 1159 people with MS in the US and 1172 healthy people.

Everyone was asked about their coffee consumption and how long they had been drinking coffee. The researchers then extrapolated out the coffee intake at and before the start of MS symptoms in those who developed the disease, compared with those who didn’t.

What they found was that the risk of MS was consistently higher among those who drank fewer cups of coffee every day – in both studies. This was even after taking into account other factors. In the Swedish study, they found that those who drank at least 900ml of coffee every day had a 28% to 30% lower risk of MS than did the non-coffee drinkers. In the American study, they found a 26% to 31% lower risk among those who drank more than 948ml daily at least five years prior to the start of symptoms.

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As they concluded, “Lower odds of MS with increasing consumption of coffee were observed, regardless of whether coffee consumption at disease onset or five or 10 years prior to disease onset was considered. In accordance with studies in animal models of MS, high consumption of coffee may decrease the risk of developing MS.”

Certainly, more studies are necessary. But, as Dr. Emma Gray, head of clinical trials at the MS Society said, “While more studies are needed in this area, we welcome any research that offers new insights into risk factors for MS.”

In a fascinating new study from Washington University School of Medicine in St. Louis, the greatest benefit of weight loss in obese patients apparently comes from losing just 5% of their body weight. Published online on February 22 in the journal Cell Metabolism, they found that this relatively small weight loss lowered patients’ risk for diabetes and cardiovascular disease while improving the metabolic function in liver, fat and muscle tissue.

As the principal investigator Samuel Klein, MD, director of Washington University’s Center for Human Nutrition said, “Our findings demonstrate that you get the biggest bang for your buck with 5 percent weight loss. The current guidelines for treating obesity recommend a 5 to 10 percent weight loss, but losing 5 percent of your body weight is much easier than losing 10 percent. So it may make sense for patients to aim at the easier target.”

The study included asking 40 obese individuals to either maintain their body weight or start a diet to lose 5-15% of their body weight. This is thought to be the first time that a trial has separated weight loss outcomes and distinguished between a 5% loss and a 10% or greater loss.

With the 19 volunteers who lost 5% of their body weight, the function of insulin-secreting beta cells improved, the insulin sensitivity in fat tissues improved, the liver and skeletal muscle tissue improved and there was a decrease in total body fat and less fat in the liver.

For the nine participants who then continued to lose weight until the 15% mark, they had some improvements but not in all areas. Their bet cell function and insulin sensitivity in muscle tissue improved, but neither their insulin sensitivity in the liver or the adipose tissue continued to improve.
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What they found from this is that, as Klein explained, “Muscle tissue responds much more to continued weight loss, but liver and adipose tissue have pretty much achieved their maximum benefit at 5 percent weight loss.”

Certainly, more research is needed by the initial findings are quite interesting. Klein would like to also study people who have diabetes.

Obviously, having a healthy weight is important. But it’s interesting to note how much the first 5% of that weight loss can have an impact.

Interestingly, it might be more important for you to chat about your latest book than to get your body moving, say researchers looking at retirement needs. Scientists have found that maintaining social links in old age may help you to live longer.

Tracking a group of 424 English men and women during their first six years of retirement, the scientists found a six-fold difference in mortality rates between the people who were members of at least two social groups from before their retirement and those who stopped attending clubs. The researchers, from the University of Queensland in Australia published their findings in BMJ Open, a UK medical journal.

As they explained, “Retiring from work constitutes a major life transition that most people experience at some point in the course of their life, posing significant challenges to health and wellbeing.”

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They found that the number of social relationships that people maintain during their retirement can have more of an impact on life expectancy than exercise, smoking or drinking.

The overall take-away, as explained by the researchers was that: “Practical interventions should focus on helping retirees to maintain their sense of purpose and belonging by assisting them to connect to groups and communities that are meaningful to them.”