Tag: Autism

Fascinating Study Links 5 Disorders

Massachusetts General Hospital in Boston has just concluded a fascinating study that could revolutionize how doctors look at autism, ADHD, bipolar disorder, depression and schizophrenia. In their study, they have found that these five disorders share a common genetic root.

As study leader Dr. Jordan Smoller told NBC News, “We have been able to discover specific genetic variants that seem to overlap among disorders that we think of as very clinically different.”

They found markers that were more common in people with one of these disorders than with others. They also found mutations in two genes that help to govern the balance of calcium in the brain cells.

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Scientists came to their conclusions after looking at the genetic code of more than 33,000 patients with mental disorders and 27,888 patients without these issues. It was actually the most comprehensive study on genetic links to psychiatric illness that was ever conducted.

Dr Smoller explained some of the ramifications of the study. As he said, “Significant progress has been made in understanding the genetic risk factors underlying psychiatric disorders. Our results provide new evidence that may inform a move beyond descriptive syndromes in psychiatry and towards classification based on underlying causes.”

Infant Therapy May Help Prevent Full-Blown Autism

In an effort to pre-empt the development of autism in children at risk, the MIND Institute at the University of California at Davis is administering intense therapy to children as young as 6 months old who have shown some signs of autistic behaviors during evaluations.

Today there is no concrete diagnosis of autism in children younger than two years old. The problem is that by this age the establishment of the illness is too far along for therapy to make enough of an impact. David Mandell, associate director of the Center for Autism Research at the Children’s Hospital of Philadelphia explains how the early intervention might acutally be able to prevent the eventual development of full-blown autism.

“What you ultimately might be doing is preventing a certain proportion of autism from ever emerging. I’m not saying you’re curing these kids, but you may be changing their developmental trajectory enough by intervening early enough that they never go on to meet criteria for the disorder. And you can’t do that if you keep waiting for the full disorder to emerge.”
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The infant therapy which MIND utilizes relies upon games and pretend-play which was developed for toddlers. In order to be of use to such young children, the focus is instead on stimulating the normal behaviors which 6 month-old children engage in, such as babbling, and the routine stimulations which take place at bath-time, feeding time, dressing and diaper-changing. Games like peek-a-boo or tickling are emphasized, in the hope of blocking the debilitating behaviors associated with autism.

Autism and A Mother’s Courage

Autism is a poorly understood illness which effects the proper functioning of certain parts of the nervous system. To a large variation in degree, those affected have difficulty with ordinary social interactions and communication abilities. These deficits are frequently accompanied by characteristic repetitive motions, such as swaying to and fro, or spinning in circles, which make the inability to communicate and interact more pronounced and difficult.

Parents of children with autism usually begin to notice symptoms in the first two or so years of life, although there have been many cases of a children appearing to develop normally at first and then suddenly regressing to a more autistic type of development. There is a range in the spectrum of the disorder, with two other named diseases contained within the definition of autism. Those are Asperger syndrome and Pervasive Developmental Disorder-Not Otherwise Specified (PDD-NOS.)

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Although many, if not most children with autism cannot truly be self-sufficient when they reach adulthood, there have been cases of people with autism becoming successful in life.  For parents living with children with this often devastating illness, life can become a highly challenging journey. Recently a film about the struggles of families affected by autism has been produced to high acclaim. Take a look for yourself at A Mother’s Courage, and learn a little bit more about this poorly understood, yet catastrophic illness.